If you are sourcing 4-Butylphenylboronic acid CAS 145240-28-4, you are typically looking for an alkyl-substituted aryl boronic acid for carbon–carbon bond formation, especially Suzuki–Miyaura coupling. I identify this material by its CAS number, chemical structure, purity requirement, packaging needs, and intended synthesis route rather than by the name alone. Its molecular formula is commonly represented as C10H15BO2, with a calculated molecular weight of approximately 178.04 g/mol. As Maison Chemical, we support buyers with product identification, specification review, documentation coordination, and export-oriented supply planning.
If you want to learn more, please visit our website.
This guide is intended for pharmaceutical and agrochemical research teams, medicinal chemistry laboratories, specialty chemical manufacturers, procurement departments, and distributors evaluating 4-Butylphenylboronic acid. It is also useful for buyers comparing laboratory-scale material with larger-volume procurement. I focus on practical sourcing questions while keeping product claims limited to information that should be confirmed through current technical documentation.
4-Butylphenylboronic acid is an aryl boronic acid in which a butyl group is positioned para to the boronic acid group on a benzene ring. The CAS Registry Number is 145240-28-4, and the commonly used molecular formula is C10H15BO2. Its approximate molecular weight is 178.04 g/mol, which buyers can use for stoichiometric planning and analytical method development.
The boronic acid group is the key reactive feature of this molecule. In palladium-catalyzed Suzuki–Miyaura coupling, aryl boronic acids can react with suitable aryl or vinyl halides and related electrophilic partners to form new carbon–carbon bonds. Actual performance depends on the reaction substrate, catalyst, base, solvent, water content, temperature, reaction time, and purification method, so I recommend treating the material as a route-specific reagent rather than assuming universal reaction performance.
The para-butyl group provides a nonpolar alkyl substituent on the aromatic ring. This structural feature may help chemists introduce a hydrophobic fragment into an intermediate or final compound, but the practical effect depends on the complete molecular structure and the reaction system. The compound should therefore be evaluated by structure, purity, solubility behavior, and compatibility with the buyer’s synthetic route.
A commercial specification should distinguish confirmed product data from buyer-defined acceptance criteria. At minimum, I recommend reviewing the chemical name, CAS number, molecular formula, molecular weight, assay method, appearance, identification method, water content, residual solvents, and impurity profile. A certificate of analysis should be matched to the batch supplied rather than treated as a generic document.
| Specification Area | What to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS 145240-28-4, structure, formula, and analytical identification | Prevents substitution with a positional isomer or similarly named boronic acid |
| Assay | Buyer-required purity target, such as 98% or another agreed level | Influences stoichiometry, impurity control, and downstream reproducibility |
| Physical description | Color, form, and appearance stated in the current specification | Provides a basic incoming-quality check |
| Moisture and solvents | Water content and residual solvent limits where relevant | Can affect sensitive coupling reactions and analytical results |
| Packaging and storage | Container type, protection from contamination, and recommended storage conditions | Supports stability during warehouse handling and transport |
The exact appearance, assay, impurity limits, and shelf-life statement should be confirmed from the applicable batch documentation. I do not recommend using a marketplace listing or an old specification as the sole basis for a regulated or scale-up purchase. If the material is intended for a sensitive route, buyers should also ask whether the supplier can provide chromatographic data and any available elemental or moisture analysis.
The principal use of 4-Butylphenylboronic acid is as an aryl component in cross-coupling chemistry. It may be selected when a synthetic route requires installation of a 4-butylphenyl group onto a suitable coupling partner. Researchers should confirm that the chosen catalyst and base system are compatible with the substrate, because boronic acid behavior can vary across different reaction conditions.
In medicinal chemistry, this building block can be considered when a project requires rapid preparation of analogues containing a para-butyl-substituted aromatic unit. Its value is typically associated with structural diversification rather than with a standalone end-use product. Final compound performance cannot be inferred from the building block alone, and all biological or application-specific conclusions require testing of the finished molecule.
Process chemists may evaluate the material during route scouting, impurity studies, or intermediate manufacture. At this stage, lot-to-lot consistency, packaging, analytical traceability, and supply continuity can be as important as the nominal assay. For larger campaigns, I recommend requesting a representative sample before confirming a full-volume order.
If you are looking for more details, kindly visit Maison Chemical.
Start by specifying whether the material is needed for discovery research, method development, process development, or commercial manufacturing. A small research project may prioritize availability and flexible pack sizes, while a production route usually requires stronger controls on documentation, impurity limits, and supply continuity. The intended use determines which specification elements deserve the most attention.
Define the minimum assay, identification requirements, moisture limit, residual solvent expectations, and packaging format before requesting quotations. If a buyer needs an assay target of 98% or higher, that target should appear in the quotation or purchase specification rather than being assumed. I also advise identifying prohibited solvents or elemental impurities when the compound will enter a tightly controlled downstream process.
Price should be assessed together with pack size, minimum order quantity, sample policy, lead time, documentation, shipping method, and payment terms. A low unit price may not represent the best value if the supplier cannot support the required batch size or provide usable quality records. For export procurement, confirm labeling, outer packaging, customs information, and the responsibilities of each party before dispatch.
Pricing for specialty boronic acids can change according to assay, batch size, raw-material availability, packaging, analytical requirements, and destination. I recommend requesting separate quotations for sample, development, and production quantities because the commercial conditions may differ substantially. A supplier should state whether the quoted lead time is based on available stock, scheduled production, or custom preparation.
Minimum order quantity is not only a commercial issue; it also affects inventory risk and material aging. Buyers should avoid purchasing more than they can properly store or consume within their project timeline. Before confirming an order, ask for the quotation validity period, expected production or dispatch date, shipping terms, and the documents that will accompany the material.
A reliable supplier should be able to identify the product consistently by CAS 145240-28-4 and provide a clear technical specification. I recommend checking whether the supplier can explain its quality-control workflow, batch documentation, packaging method, and response process for technical questions. Claims about manufacturing status, certifications, stock, or regulatory compliance should be verified against current documents rather than accepted without review.
At Maison Chemical, I help buyers translate a chemical requirement into a practical sourcing specification for 4-Butylphenylboronic acid. Our support can include product identification, quantity-based quotation, sample coordination, document review, packaging discussion, and export shipment planning. The final offer should be based on the required grade, quantity, destination, documentation, and delivery schedule.
For development and manufacturing customers, I recommend sharing the intended application, approximate annual demand, target assay, preferred pack size, and required delivery window. This information allows us to assess the most suitable supply approach without making unsupported assumptions about stock or performance. Where a project is sensitive to impurities or moisture, those requirements should be communicated before quotation and sampling.
4-Butylphenylboronic acid CAS 145240-28-4 is a practical aryl boronic acid building block for synthetic routes that require a 4-butylphenyl fragment, particularly in Suzuki–Miyaura coupling. The correct purchasing decision depends on more than the chemical name: identity, assay, impurity profile, documentation, packaging, quantity, and delivery capability must all match the project. Its suitability should be confirmed through route evaluation and appropriate laboratory testing.
Your next step should be to prepare a concise purchasing brief covering quantity, purity target, analytical documents, packaging, destination, and required delivery date. Send those requirements to Maison Chemical for a tailored quotation and technical review. We can then help you determine whether the available grade and supply plan are appropriate for your research, process-development, or production needs.
Want more information on 4-Butylphenylboronic acid CAS 145240-28-4? Feel free to contact us.